侯美丽，女，中国党员，博士研究生，四川轻化工大学医学院讲师。本人致力于小分子前药纳米药物递送系统的设计、合成及其在肿瘤精准治疗领域的应用，具备理论及实践基础。主要研究方向包括：（1）刺激响应性前药分子的设计与合成；（2）多功能无载体纳米药物在肿瘤联合治疗方面的应用；（3）智能型化学医用材料的构建及应用研究。
一、学习与工作经历：
2024-至今，四川轻化工大学，讲师
2018-2024，重庆大学，化学化工学院，化学工程与技术，工学博士
2015-2018，西南大学，材料与能源学部，洁净能源科学，理学硕士2011-2015，山西师范大学，化学与材料科学学院，化学，理学学士
二、学术论文：
1. Meili Hou, Mengjie Ye, Lei Liu, Mingchuan Xu, Hongmei Liu, Hengbo Zhang, Yangfeng Li*, Zhigang Xu*, Baosheng Li*. Azide-Locked Prodrug Co-Assembly into Nanoparticles with Indocyanine Green for Chemophotothermal Therapy. Molecular Pharmaceutics, 2022, 19, 9, 3279–3287.
2. Meili Hou, Shanshan Li, Zhigang Xu*, Baosheng Li*. A Reduction-responsive Amphiphilic Methotrexate-Podophyllotoxin Conjugate for Targeted Chemotherapy. Chemistry - An Asian Journal, 2019, 14, 21, 3840-3844.
3. Meili Hou,Yong-E Gao,Xiaoxiao Shi,Shuang Bai,Xiaoqian Ma, Baosheng Li,Bo Xiao,Peng Xue,Yuejun Kang*,Zhigang Xu*. Methotrexate-Based Amphiphilic Prodrug Nanoaggregates for Co-Administration of Multiple Therapeutics and Synergistic Cancer Therapy. Acta Biomaterialia. 2018, 77, 228-239.
4. Meili Hou, Peng Xue, Yong-E Gao, Xiaoqian Ma, Shuang Bai, Yuejun Kang*, Zhigang Xu*. Gemcitabine-camptothecin conjugates: A Hybrid Prodrug for Controlled Drug Release and Synergistic Therapeutic, Biomaterials Science, 2017, 5, 9, 1889-1897.
5. Zhigang Xu*, Meili Hou, Xiaoxiao Shi, Yong-E Gao, Peng Xue, Shiying Liu, Yuejun Kang*. Rapidly Cell-Penetrating and Reductive Milieu-Responsive Nanoaggregates Assembled From An Amphiphilic Folate-Camptothecin Prodrug for Enhanced Drug Delivery and Controlled Release, Biomaterials Science, 2017, 5, 3, 444-454.
6. Xiaoxiao Shi, Meili Hou, Xiaoqian Ma, Shuang Bai, Tian Zhang, Peng Xue, Xiaoli Zhang*, Gang Liu, Yuejun Kang, Zhigang Xu*, Starburst Diblock Polyprodrugs: Reduction-Responsive Unimolecular Micelles with High Drug Loading and Robust Micellar Stability for Programmed Delivery of Anticancer Drugs. Biomacromolecules, 2019, 20, 3, 1190-1202.
7. Xiaoxiao Shi, Meili Hou, Shuang Bai, Xiaoqian Ma, Yong-E Gao, Bo Xiao, Peng Xue, Yuejun Kang*, Zhigang Xu*, Chang Ming Li, Acid-Activatable Theranostic Unimolecular Micelles Composed of Amphiphilic Star-like Polymeric Prodrug with High Drug Loading for Enhanced Cancer Therapy, Molecular Pharmaceutics, 2017, 14, 11, 4032-4041.
8. Rui Wang, Meili Hou, Zhigang Xu, Luxi Tan, Cheng Zhong, Linna Zhu*, A New Red Fluorophore with Aggregation Enhanced Emission by An Unexpected "One-Step" Protocol, RSC Advances, 2018, 8, 33, 18327-18333.
9. Shuang Bai, Meili Hou, Xiaoxiao Shi, Jiucun Chen, Xiaoqian Ma, Yong-E Gao, Yajun Wang, Peng Xue, Yuejun Kang*, Zhigang Xu*, Reduction-Active Polymeric Prodrug Micelles Based On α-Cyclodextrin Polyrotaxanes for Triggered Drug Release And Enhanced Cancer Therapy, Carbohydrate Polymers, 2018, 193, 153-162.
电子邮箱：houmeili@suse.edu.cn
